Endothelin Receptor
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Endothelin Receptor Inhibitors
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Endothelin Receptor Agonists
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Endothelin Receptor Antagonists
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Endothelin Receptor Modulator
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Endothelin Receptor Control
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Endothelin Receptor Ligands
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Endothelin Receptor Related Products (95)
Related Products (95)
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DEDN6526A Antibody
0 ImagesCat. No.: HY-P990573Synonyms: RG-7636DEDN6526A (RG-7636) is a humanized antibody expressed in CHO cells, targeting ETBR. DEDN6526A (RG-7636) has a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for DEDN6526A (RG-7636) can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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ETA antagonist 1
0 ImagesCat. No.: HY-112264CAS No.: 161801-60-1ETA antagonist 1 is a ETA selective antagonist with an IC50 of 0.08 μM.
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JKC 302
0 ImagesCat. No.: HY-P3228CAS No.: 153982-38-8JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring.
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Rendomab B4
0 ImagesCat. No.: HY-P991964Synonyms: Rendomab-B49Rendomab B4 (Rendomab-B49) is a monoclonal antibody targeting ETB. Rendomab B4 preferentially binds to ETB in the active conformational state and exhibits selectivity for ETB on melanoma cells. Rendomab B4 inhibits the G protein-dependent phospholipase C (PLC) pathway, blocks ET-3-induced Gαi/o-mediated inhibition of adenylate cyclase, and does not affect the activation of the ERK1/2 pathway. Rendomab B4 is applicable to melanoma-related research.
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PD 142893
0 ImagesCat. No.: HY-P2057CAS No.: 143037-36-9PD 142893 is a endothelin-B receptor antagonist.
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K-8794
0 ImagesCat. No.: HY-157658CAS No.: 180577-26-8K-8794 is an orally active selective endothelin receptor ETB antagonist that can be used in research on cardiovascular diseases.
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Big endothelin-3 (Human, 1-41 amide)
0 ImagesCat. No.: HY-P11605CAS No.: 133551-97-0Big endothelin-3 (Human, 1-41 amide) is a precursor molecule of the Endothelin-3 (ET-3) peptide composing of 41 amino acids.
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Sarafotoxin S6b
0 ImagesCat. No.: HY-P3433CAS No.: 120972-53-4Sarafotoxin S6b is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin S6b can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively.
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Cgs 27830
0 ImagesCat. No.: HY-182561CAS No.: 155485-56-6Cgs 27830 is an endothelin receptor antagonist with 20-fold higher selectivity for ET-A receptors over ET-B receptors. Cgs 27830 blocks activity of ET-A and ET-B receptors. Cgs 27830 does not alter basal vascular tone in the ovine fetal pulmonary circulation. Cgs 27830 prevents big-endothelin-1-induced pulmonary vasoconstriction in late gestation fetal lambs.
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Lactokinin
0 ImagesCat. No.: HY-P11942CAS No.: 132160-04-4Lactokinin is an Endothelin-1 (HY-P0202) release inhibitor and ACE inhibitor, with an ACE IC50 value of 29 μM. Lactokinin binds to bovine β-lactoglobulin variant A to form a non-covalent complex, which delays its hydrolysis by chymotrypsin, as well as by pepsin/chymotrypsin, in vitro. Lactokinin can be used in research related to hypertension.
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Sulfatroxazole
0 ImagesCat. No.: HY-105829CAS No.: 23256-23-7Synonyms: IsosulfafurazoleSulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC50=0.26 μM).
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BE 24566B
0 ImagesCat. No.: HY-W781265CAS No.: 149466-04-6Synonyms: L-755,805BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC50s=11 and 3.9 μM for ETA and ETB receptors, respectively).
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Sparsentan-d5
0 ImagesCat. No.: HY-17621SCAS No.: 1801597-09-0Synonyms: RE-021-d5; DARA-a-d5Sparsentan-d5 is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.
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Daglutril
0 ImagesCat. No.: HY-10282CAS No.: 182821-27-8Daglutril is a compound with the potential to regulate cytokine-induced endothelin-1 production in astrocytes. In studies, it has an inhibitory effect on the production of endothelin-1 induced by some cytokines and can be used as a tool to screen compounds that inhibit endothelin-1 production in astrocytes.
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PD 156252
0 ImagesCat. No.: HY-P10151CAS No.: 175592-65-1PD 156252 is a hexapeptide that is a highly potent endothelin (ET) antagonist. PD 156252 has enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 and 40 nM, respectively.
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[Ala2] Endothelin-3, human
![[Ala2] Endothelin-3, human](https://file.medchemexpress.com/product_pic/hy-p3571.gif "Click to View [Ala2] Endothelin-3, human Product Detail")
0 ImagesCat. No.: HY-P3571CAS No.: 2243207-08-9[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3) where substitution of Ala for Cys residues. TE-3 is a vasoactive peptide, produced by human rhabdomyosarcoma cell lines, whereas it is not expressed by human sarcoma cell lines of non-muscle origin. ET-3 acts as a paracrine factor, since it promotes migration of endothelial cells.
